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KMID : 0371319960500030447
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Journal of the Korean Surgical Society
1996 Volume.50 No. 3 p.447 ~ p.456
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Adrenal Tumors Originating from the Cortex of the Adrenal Gland - 3 cases reports -
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Abstract
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The adrenal gland is a composite endocrine organ with a bipartite embryologic origin. The adrenal cortex synthesizes and secretes major glucocorticoids, mineralocorticoids, androgens and small amounts of estrogens. Neoplastic conditions affecting
the
adrenal gland may be associated with excess secretion of the various hormones, producing a wide variety of clinical syndromes.
Adrenal adenoma is a benign neoplasm of adrenocortical cells that resembles normal cells histologically but may possess functional autonomy and produce hypercortisolism and hyperaldosteronism. Adrenocortical carcinoma is a malignant neoplasm of
adrenocortical cells demonstrating partial or complete histologic and functional differentiation. Adrenocortical carcinomas especially in nonfunctioning carcinoma are rare neoplasms and comprise only 0l05% to 0.20% of all cancer. We experienced
two
adrenal adenomas and one nonfunctioning adrenocortical carcinoma during one recent year. Unilateral adrenalectomies were performed in all three patients. The clinicopathologic findings revealed nonfunctioning, adrenocortical carcinoma, a
Cushing's-like
syndrome due to cortisol secreting adrenal adenoma and primary aldosteronism due to aldosterone secreting adrenal adenoma.
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